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Biophysics

Data from R.R.P. Machado and colleagues advance knowledge in biophysics

Published in TB and Outbreaks Week, January 6th, 2009

According to a study from Brazil, "An interferometer that measures the refractive index changes due to bacterial metabolism is described."

"The apparatus permits simultaneous and real time measurement of bacterial growth in several samples of slowly growing mycobacteria. The error sources are discussed and the sensitivity of the apparatus is tested," wrote R.R.P. Machado and colleagues.

The researchers concluded: "For the species Mycobacterium bovis BCG and M. smegmatis, a relation between refractive index change and bacterial concentration is determined experimentally and the time constant of bacterial growth is measured."

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