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TB & Outbreaks Week

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Bacteremia



New research on bacteremia from Massachusetts General Hospital summarized



January 20th, 2009

"Relapsing fever (RF) is a spirochetal infection characterized by periods of sickness with fever at time of high bacteremia that alternate with afebrile periods of relative well being during low bacteremia. Patients with epidemic RF who are doing relatively well have extraordinarily high levels of interleukin-10 (IL-10) in the circulation," scientists in the United States report.

"We investigated the possibility that IL-10 plays an important protective role in this infection using wild-type and IL-10-deficient mice inoculated with virulent serotype 2 of the RF spirochete Borrelia turicatae. During peak bacteremia there was increased systemic production of IL-10 that...


Source: TB & Outbreaks Week (2009-01-20)

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