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Escherichia Coli
Study results from E. Strauch and colleagues update understanding of Escherichia coli
January 20th, 2009
"The production of Shiga toxin (Stx) (verocytotoxin) is a major virulence factor of Escherichia coli O157: H7 strains (Shiga toxin-producing E. coli [STEC] O157). Two types of Shiga toxins, designated Stx1 and Stx2, are produced in STEC O157," scientists in Berlin, Germany report. "Variants of the Stx2 type (Stx2, Stx2c) are associated with high virulences of these strains for humans. A bacteriophage designated 2851 from a human STEC O157 encoding the Stx2c variant was described previously. Nucleotide sequence analysis of the phage 2851 genome revealed 75 predicted coding sequences and indicated a mosaic structure typical for lambdoid phages. Analyses of free phages and...
Source: TB & Outbreaks Week (2009-01-20)
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