TB & Outbreaks Week
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of TB & Outbreaks Week
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Life Sciences
Research on life sciences detailed by R. Pommer and co-authors
January 20th, 2009
"Leber's hereditary optic neuropathy (LHON) is a maternally inherited mitochondrial disorder, leading to a selective loss of retinal ganglion cells (RGC) and degeneration of the optic nerve, which results in severe Visual impairment or even blindness. The primary causes are point mutations of the mitochondrial DNA (mtDNA), associated with aminoacid exchanges in complex I of the electron transport chain (ETC), which are thought to disturb oxidative ATP generation in the mitochondria," scientists writing in the journal Clinical Neuropathology report. "The major side effect of the antibiotic ethambutol, commonly used in tuberculosis therapy, is a retinopathy, which...
Source: TB & Outbreaks Week (2009-01-20)
|
