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Life Sciences
Study findings on life sciences are outlined in reports from C. Dumestreperard and colleagues
January 20th, 2009
"Innate immunity is the major host defense against invasive aspergillosis. To determine whether the collectin mannan-binding lectin (MBL) is involved in the initial protective immunity through complement activation against opportunistic fungal infections caused by Aspergillus, we performed in vitro studies on 29 different strains of Aspergillus conidia from five different species," researchers in Grenoble, France report. "Incubation of Aspergillus conidia in human normal serum leads to activation of the alternative pathway, whereas neither the classical nor the lectin pathways through C4 and C2 cleavage are activated. Complement response to conidia was investigated...
Source: TB & Outbreaks Week (2009-01-20)
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