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TB & Outbreaks Week

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Obesity



Reports from Johns Hopkins University, Medical Department add new data to research in obesity



January 20th, 2009

"The American diet, especially that of adolescents, contains highly palatable foods of high-energy content and large amounts of high-fructose sweeteners. These factors are believed to contribute to the obesity epidemic and insulin resistance," scientists in the United States report.

"Previous investigations revealed that the central metabolism of glucose suppresses food intake mediated by the hypothalamic AMP-kinase/malonyl-CoA signaling system. Unlike glucose, centrally administered fructose increases food intake. Evidence presented herein indicates that the more rapid initial steps of central fructose metabolism deplete hypothalamic ATP level, whereas the slower...


Source: TB & Outbreaks Week (2009-01-20)

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