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TB & Outbreaks Week

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Tuberculosis



Data on tuberculosis published by researchers at Federal University



January 20th, 2009

According to recent research published in the American Journal of Respiratory and Critical Care Medicine, "Linezolid, the first oxazolidinone approved for clinical use, has effective in vitro and promising in vivo activity against Mycobacterium tuberculosis. To evaluate the early and extended early bactericidal activity of linezolid in patients with pulmonary tuberculosis."

"Randomized open label trial. Thirty patients with newly diagnosed smear-positive pulmonary tuberculosis (10 per arm) were assigned to receive isoniazid (300 mg daily) and linezolid (600 mg twice daily or 600 mg once daily) for 7 days. Sputum for quantitative culture was collected for 2 days...


Source: TB & Outbreaks Week (2009-01-20)

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