TB & Outbreaks Week
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Life Sciences
Scientists at University of Texas target life sciences
January 27th, 2009
"There is a pressing need for antiviral agents that are effective against multiple classes of viruses. Broad specificity might be achieved by targeting phospholipids that are widely expressed on infected host cells or viral envelopes," scientists writing in the journal Nature Medicine report. "We reasoned that events occurring during virus replication (for example, cell activation or preapoptotic changes) would trigger the exposure of normally intracellular anionic phospholipids on the outer surface of virus-infected cells. A chimeric antibody, bavituximab, was used to identify and target the exposed anionic phospholipids. Infection of cells with Pichinde virus...
Source: TB & Outbreaks Week (2009-01-27)
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