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TB & Outbreaks Week

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Apoptosis



New apoptosis data have been reported by researchers at University of East London



January 27th, 2009

"Leishmania parasites invade host macrophages, causing infections that are either limited to skin or spread to internal organs. In this study, 3 species causing cutaneous leishmaniasis, L. major, L. aethiopica and L. tropica, were tested for their ability to interfere with apoptosis in host macrophages in 2 different lines of human monocyte-derived macrophages (cell lines THP-1 and U937) and the results confirmed in peripheral blood mononuclear cells (PBMC)," researchers in London, the United Kingdom report.

"All 3 species induced early apoptosis 48 It after infection (expression of phosphatidyl serine on the outer membrane). There were significant increases in the...


Source: TB & Outbreaks Week (2009-01-27)

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