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DNA Research
Study results from A. Alborzi et al provide new insights into DNA research
February 3rd, 2009
"Visceral leishmaniasis (VL), caused by Leishmania infantum, is endemic in southern Iran. To detect asymptomatic individuals, we used kinetoplast DNA (kDNA) polymerase chain reaction (PCR)-ELISA methods on 388 blood samples of healthy persons in two endemic loci and compared the results with the leishmanin skin test (LST) and the immunofluorescent antibody test (IFAT). kDNA PCR, LST, and IFAT were positive in 95(24.5%), 132(34%), and 212 (54.6%) cases, respectively," researchers in Iran report. "Fifty-five (21.4%) individuals that were LST negative were PCR positive. All PCR-positive individuals had a titer of >= 1:20, whereas 45% of those that were IFAT positive...
Source: TB & Outbreaks Week (2009-02-03)
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