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TB & Outbreaks Week

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Drug Resistance



Study findings from Harvard University provide new insights into drug resistance



February 3rd, 2009

"To control the antibiotic resistance epidemic, it is necessary to understand the distribution of genetic material encoding antibiotic resistance in the environment and how anthropogenic inputs, such as wastewater, affect this distribution. Approximately two-thirds of antibiotics administered to humans are beta-lactams, for which the predominant bacterial resistance mechanism is hydrolysis by beta-lactamases," researchers in the United States report.

"Of the beta-lactamases, the TEM family is of overriding significance with regard to diversity, prevalence, and distribution. This paper describes the design of DNA probes universal for all known TEM beta-lactamase genes...


Source: TB & Outbreaks Week (2009-02-03)

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