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TB & Outbreaks Week

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Immunization



New immunization study findings have been published by N. Paran and colleagues



February 3rd, 2009

According to recent research from Langen, Germany, "Decades after the cessation of smallpox vaccination, the potential of the deliberate release of pathogenic orthopoxviruses has forced a reconsideration of using these extremely efficient human vaccines. Scenarios of sudden biothreats have prompted demand for rapidly protective vaccination."

"However, the feasibility of short-term vaccination ( i. e., vaccination shortly before exposure) with vaccinia virus (VACV) is uncertain. We tested the rapid protective capacity of vaccines based on VACV strain Lister (VACV-Lister) and on modified VACV Ankara (MVA) in different mouse models, comparing lethal infections with VACV...


Source: TB & Outbreaks Week (2009-02-03)

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