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Legionnaire Disease
Study data from Yale University provide new insights into legionnaire disease
February 10th, 2009
"The immune system must discriminate between pathogenic and nonpathogenic microbes in order to initiate an appropriate response. Toll-like receptors (TLRs) detect microbial components common to both pathogenic and nonpathogenic bacteria, whereas Nod-like receptors (NLRs) sense microbial components introduced into the host cytosol by the specialized secretion systems or pore-forming toxins of bacterial pathogens," scientists writing in the journal Plos Pathogens report. "The host signaling pathways that respond to bacterial secretion systems remain poorly understood. Infection with the pathogen Legionella pneumophila, which utilizes a type IV secretion system...
Source: TB & Outbreaks Week (2009-02-10)
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