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TB & Outbreaks Week

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Meningococcal Disease



Study findings from Radboud University provide new insights into meningococcal disease



February 10th, 2009

According to a study from Netherlands, "The long pentraxin 3 (PTX3) is an important element of the innate immune system and has potential as a diagnostic tool in inflammatory conditions. We studied PTX3 in patients admitted to an intensive care unit with severe meningococcal disease and compared it with the short pentraxin C-reactive protein (CRIP)."

"Twenty-six patients with meningococcal disease were studied, 17 patients presented with meningococcal septic shock (shock group), and 9 patients presented with meningococcal meningitis or bacteremia (no-shock group). Pentraxin 3 and CRP were measured by enzyme-linked immunosorbent assay. High plasma concentrations of PTX3...


Source: TB & Outbreaks Week (2009-02-10)

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