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Hemorrhagic Fever
Data from Fourth Military Medical University provide new insights into hemorrhagic fever
February 17th, 2009
According to recent research published in the Journal of Infectious Diseases, "The cellular immune response to Hantaan virus (HTNV) is incompletely understood, especially in humans. To investigate the cellular immunity during acute HTNV infection, the magnitude of the CD4(+) and CD8(+) T cell responses to HTNV nucleocapsid protein was quantitated by direct ex vivo interferon-gamma(IFN-gamma) enzyme-linked immunosorbent spot analysis, using an array of overlapping peptides." "We found that the combined frequencies of HTNV-specific T cells at the earliest available time point (5-8 days after fever onset) were significantly higher in patients who had mild or...
Source: TB & Outbreaks Week (2009-02-17)
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