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TB & Outbreaks Week

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Hemorrhagic Fever



Study results from Dalhousie University in the area of hemorrhagic fever published



February 17th, 2009

According to recent research from Halifax, Canada, "Severe forms of dengue virus disease, known as dengue hemorrhagic fever and dengue shock syndrome, result from an aberrant immune response involving antibody-dependent enhancement of infection, thrombocytopenia, and a loss of vascular integrity, culminating in hemorrhage, shock, and in some cases, death. Several studies have indicated that dengue virus infection results in the induction of apoptosis of certain cells believed to be contributory players in dengue pathogenesis."

"However, none have specifically examined the role of antibody enhancement in the context of induction of apoptosis. Here, we show that...


Source: TB & Outbreaks Week (2009-02-17)

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