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TB & Outbreaks Week

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Infectious Disease



Data on infectious disease discussed by researchers at University of Georgia



February 17th, 2009

"Elevated immunoglobulin E (IgE) levels are often associated with resistance to reinfection in human schistosomiasis. However, Although B cells are the source of schistosome-specific IgE, little is known about B cell subsets or their functions in this infection," researchers in the United States report.

"We evaluated B cells and their expression of the low-affinity IgE receptor (CD23) in a unique cohort of men occupationally exposed to Schistosoma mansoni and longitudinally followed up through multiple treatments with praziquantel, cures, and reinfections. Resistance levels were calculated on the basis of documented water exposure and reinfection data over many years....


Source: TB & Outbreaks Week (2009-02-17)

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