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Leishmaniasis

Research from M.F. Nogueira and co-authors provides new data about leishmaniasis

Published in TB and Outbreaks Week, February 17th, 2009

According to a study from Sao Paulo, Brazil, "American tegumentary leishmaniasis presents as two major clinical forms: localized cutaneous leishmaniasis (LCL) and mucocutaneous leishmaniasis (MCL). The immune response in leishmaniasis is efficiently evaluated by the response to Leishmania antigen through the Montenegro skin test (MST)."

"Both LCL and MCL present positive response to MST, indicating that the patients present cell-mediated immunity against the parasite-Leishmania. In spite of the presence of immunity in MCL, this is not sufficient to stop disease progression and prevent resistance to treatment. In this study we demonstrated interleukin (IL) 2, 4, 5 and...

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