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TB & Outbreaks Week

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Atorvastatin



Researchers from University of Barcelona report details of new studies and findings in the area of atorvastatin



February 17th, 2009

According to a study from Barcelona, Spain, "High fructose intake contributes to the overall epidemic of obesity and metabolic disease. Here we examined whether atorvastatin treatment blocks the activation of the carbohydrate response element binding protein (ChREBP) in the fructose-fed rat."

"Fructose feeding increased blood pressure (21%, P< 0.05), plasma free fatty acids (59%, P< 0.01), and plasma triglyceride levels (129%, P< 0.001) compared with control rats fed standard chow. These increases were prevented by atorvastatin. Rats fed the fructose-rich diet showed enhanced hepatic messenger RNA (mRNA) levels of glycerol-3-phosphate acyltransferase (Gpat1)...


Source: TB & Outbreaks Week (2009-02-17)

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