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Tuberculosis
Scientists at McGill University discuss research in tuberculosis
February 17th, 2009
"Interferon-gamma assays (IGRAs) are alternatives to the tuberculin skin test (TST), but IGRA conversions and reversions are not well understood. In a pilot study, we determined conversions and reversions using QuantiFERON-TB Gold In-Tube (R) (QFT) among household contacts of TB cases, and evaluated the effect of using various definitions and criteria for conversions," researchers in Montreal, Canada report. "In a cohort of 250 contacts in India, 46% were TST-positive at baseline and 54% were QFT-positive. We re-tested this cohort after 12 months. Conversion rates were estimated using several definitions. Of the 250 contacts, 205 (82%) underwent repeat testing. Among 85...
Source: TB & Outbreaks Week (2009-02-17)
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