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TB & Outbreaks Week

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Escherichia Coli



Studies from Department of Agriculture yield new information about Escherichia coli



February 24th, 2009

"To develop methods to differentiate Escherichia coli O157:H7 and related serotypes by the use of amplicon length polymorphism (ALP) analysis based on identifying DNA sequence deletions within highly homologous regions of three sequenced E. coli strains. Potential primer locations along the ancestral genomic backbone were identified and evaluated against three sequenced genomes and then applied to a reference set of pathogenic E. coli strains," scientists writing in the Journal of Applied Microbiology report.

"All 16 primer combinations generated the expected diagnostic fragments as predicted for the E. coli K12 MG1655, O157:H7 EDL933, and O157:H7B Sakai genomes....


Source: TB & Outbreaks Week (2009-02-24)

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