Arthritis

Studies from University of Maryland have provided new information about arthritis

Published in TB and Outbreaks Week, February 24th, 2009

According to recent research published in the journal Arthritis and Rheumatism, "Pretreatment of Lewis rats with soluble mycobacterial Hsp65 affords protection against subsequent adjuvant-induced arthritis (AIA). This study was aimed at unraveling the mechanisms underlying mycobacterial Hsp65-induced protection against arthritis, using contemporary parameters of immunity."

"Lewis rats were given 3 intraperitoneal injections of mycobacterial Hsp65 in solution prior to the initiation of AIA with heat-killed Mycobacterium tuberculosis. Thereafter, mycobacterial Hsp65-specific T cell proliferative, cytokine, and antibody responses were tested in tolerized rats. The...

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Source: TB and Outbreaks Week (2009-02-24)

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