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TB & Outbreaks Week

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Clinical Microbiology and Infectious Disease



Research in the area of clinical microbiology and infectious disease reported from Erasmus University



February 24th, 2009

"This study investigates aspects of the general assumption that, in bacteria, genetic variation in functionally-constrained genomic regions accumulates at a lower rate than in regions of hypermutability such as DNA repeat loci. We compared whole genome polymorphism (using high-throughput amplified fragment length polymorphism [ht-AFLP]) as well as short sequence repeat length variation (using multi-locus variable number of tandem repeat analysis [MLVA]) for 994 Staphylococcus aureus strains isolated from both healthy carriers and invasive infections," scientists in Netherlands report.

"MLVA and ht-AFLP minimum spanning trees (MSTs) were similar in their identification...


Source: TB & Outbreaks Week (2009-02-24)

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