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Flavivirus
Studies from University of Queensland further understanding of flavivirus
March 3rd, 2009
"Viral noncoding RNAs have been shown to play an important role in virus-host interplay to facilitate virus replication. We report that members of the genus Flavivirus, a large group of medically important encephalitic RNA viruses, produce a unique and highly structured noncoding RNA of 0.3-0.5 kb derived from the 3' untranslated region of the viral genome," scientists writing in the journal Cell Host & Microbe report. "Using West Nile virus as a model, we show that this subgenomic RNA is a product of incomplete degradation of viral genomic RNA by cellular ribonucleases. Highly conserved RNA structures located at the beginning of the 3' untranslated region render...
Source: TB & Outbreaks Week (2009-03-03)
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