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Fusion Proteins
Data on fusion proteins published by researchers at Fourth Military Medical University, Medical University Center
March 3rd, 2009
According to a study from Xian, People's Republic of China, "Hantaan virus (HTNV) is an Old World hantavirus associated with hemorrhagic fever with renal syndrome (HFRS). To visualize the localization of the L protein of HTNV strain 84FLi within cells, a fusion protein composed of enhanced green fluorescent protein and L protein, EGFP-L, was expressed in Vero cells." "The 273 KDa expressed fusion protein of EGFP-L localized in the perinuclear region. We also described the development of a reverse genetics system for HTNV strain 84FLi. The RNA polymerase I (pol I)-mediated transcription system was used to generate artificial viral RNA genome segments (minigenomes), which...
Source: TB & Outbreaks Week (2009-03-03)
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