Fusion Proteins
Researchers at Wake Forest University, Medical Department have published new data on fusion proteins
Published in TB and Outbreaks Week, March 3rd, 2009
According to a study from the United States, "A number of studies have clearly demonstrated that flagellin is a potent adjuvant that promotes robust immune responses when it is given with a protein antigen. In view of the potential biological and practical benefits of a recombinant protein vaccine composed of a single fusion protein containing flagellin and antigen, we have evaluated the efficacy of a fusion protein composed of flagellin and two protective antigens of Yersinia pestis (F1 and V) in eliciting protection against respiratory challenge with Y. pestis."
"Flagellin-F1-V was produced and purified in high yield under good manufacturing practices conditions. The...
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