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TB & Outbreaks Week

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Macropinocytosis



Reports by I. Malyukova and co-researchers describe recent advances in macropinocytosis



March 3rd, 2009

"Malyukova I, Murray KF, Zhu C, Boedeker E, Kane A, Patterson K, Peterson JR, Donowitz M, Kovbasnjuk O. Macropinocytosis in Shiga toxin 1 uptake by human intestinal epithelial cells and transcellular transcytosis. Am J Physiol Gastrointest Liver Physiol 296: G78-G92, 2009," scientists in the United States report.

"First published October 30, 2008; doi:10.1152/ajpgi.90347.2008.-Shiga toxin 1 and 2 production is a cardinal virulence trait of enterohemorrhagic Escherichia coli infection that causes a spectrum of intestinal and systemic pathology. However, intestinal sites of enterohemorrhagic E. coli colonization during the human infection and how the Shiga toxins are...


Source: TB & Outbreaks Week (2009-03-03)

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