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TB & Outbreaks Week

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Tuberculosis



Data on tuberculosis reported by researchers at College of Medicine



March 3rd, 2009

According to recent research published in the International Journal of Tuberculosis and Lung Disease, "Delays in identifying multidrug-resistant tuberculosis (MDR-TB) contribute to higher TB morbidity and mortality, and ongoing transmission. The line-probe assay (LiPA) is a rapid, commercially available polymerase chain reaction based assay that detects most mutations in the rpoB gene for rifampicin (RMP) resistance."

"We validated and compared this assay with conventional drug susceptibility testing (DST). We re-cultured a random sample of stored isolates known to be either RMP-resistant or RMP-susceptible according to DST (proportion method). We performed a...


Source: TB & Outbreaks Week (2009-03-03)

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