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Tuberculosis

Research from K. Kösters and colleagues provide new insights into tuberculosis

Published in TB and Outbreaks Week, March 3rd, 2009

A new study, 'Rapid diagnosis of CNS tuberculosis by a T-cell interferon-gamma release assay on cerebrospinal fluid mononuclear cells,' is now available. "Central nervous system tuberculosis remains a clinical diagnostic challenge," scientists writing in the journal Infection report.

"The ex vivo Mycobacterium tuberculosis-specific enzyme-linked immunospot assay (ELISPOT) is a novel assay for the rapid detection of M. tuberculosis-specific T-lymphocytes in the peripheral blood. However, when performed on peripheral blood, this assay cannot distinguish between active tuberculosis or latent tuberculosis infection," wrote K. Kösters and colleagues,...

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