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TB & Outbreaks Week

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Hantavirus



Data from S.L. Taylor and colleagues advance knowledge in hantavirus



March 10th, 2009

According to recent research from the United States, "Hantaviruses such as Hantaan virus (HTNV) and Andes virus cause two human diseases, hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome, respectively. For both, disease pathogenesis is thought to be immunologically mediated and there have been numerous reports of patients with elevated levels of proinflammatory and inflammatory cytokines, including tumor necrosis factor alpha (TNF-alpha), in their sera."

"Multiple viruses have developed evasion strategies to circumvent the host cell inflammatory process, with one of the most prevalent being the disruption of nuclear factor kappa B (NF-kappa B)...


Source: TB & Outbreaks Week (2009-03-10)

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