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TB & Outbreaks Week

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Infectious Disease



Scientists at State University of New York publish new data on infectious disease



March 10th, 2009

According to a study from the United States, "Acinetobacter baumannii is a bacterial pathogen of increasing medical importance. Little is known about genes important for its survival in vivo."

"Screening of random transposon mutants of the model pathogen AB307-0294 identified the mutant AB307.27. AB307.27 contained its transposon insertion in pbpG, which encodes the putative low-molecular-mass penicillin-binding protein 7/8 (PBP-7/8). AB307.27 was significantly killed in ascites (P < .001), but its growth in Luria-Bertani broth was similar to that of its parent, AB307-0294 (P = .13). The survival of AB307.27 was significantly decreased in a rat soft-tissue infection...


Source: TB & Outbreaks Week (2009-03-10)

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