TB & Outbreaks Week
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of TB & Outbreaks Week
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Life Sciences
Recent findings from University of Regensburg highlight research in life sciences
March 10th, 2009
According to a study from Regensburg, Germany, "The biological role of Langerin(+) dendritic cells (DCs) such as Langerhans cells and a subset of dermal DCs (dDCs) in adaptive immunity against cutaneous pathogens remains enigmatic. Thus, we analyzed the impact of Langerin(+) DCs in adaptive T cell-mediated immunity toward Leishmania major parasites in a Lang-DTR mouse model that allows conditional diphtheria toxin (DT)-induced ablation of Langerin(+) DCs in vivo." "For the first time, infection experiments with DT-treated Lang-DTR mice revealed that proliferation of L. major-specific CD8(+) T cells is significantly reduced during the early phase of the immune response...
Source: TB & Outbreaks Week (2009-03-10)
|
