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Meningitis
Laval University reports research in meningitis
March 10th, 2009
"Endothelial cells and macrophages are thought to play a critical role in the inflammatory response that contributes to meningitis. To investigate the interactions between Streptococcus suis and these two cell types, we developed a coculture model composed of brain microvascular endothelial cells and macrophage-like cells, and characterized the production of proinflammatory cytokines, chemokines, prostaglandin E-2 (PGE(2)), and matrix metalloproteinase 9 (MMP-9) following a challenge with bacteria," researchers in Canada report. "Streptococcus suis cells stimulated the secretion of all the inflammatory mediators as well as MMP-9 in the coculture model. Responses to S....
Source: TB & Outbreaks Week (2009-03-10)
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