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Tuberculosis
New tuberculosis research has been reported by F. Doustdar et al
March 10th, 2009
According to a study from Iran, "Considering the significant increase of isoniazid (INH) resistance in Iranian Mycobacterium tuberculosis isolates in the last few years and to investigate the prevalence and diagnostic potential of the most commonly reported mutations associated with INH resistance in Iran, we analyzed parts of the katG gene and fabG1-inhA and oxyR-ahpC regulatory regions in a sample of 48 INH-resistant and 25 INH-sensitive isolates. Mutations in the katG 315, fabG1-inhA, and oxyR-ahpC regulatory regions were detected in 58.3%, 18.7%, and 39.6% of isolates, respectively." "The R463L polymorphism in the katG gene and the ahpC46A were detected with high...
Source: TB & Outbreaks Week (2009-03-10)
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