Life Sciences

New life sciences study findings have been reported from University do Extremo Sul Catarinense

Published in TB and Outbreaks Week, March 10th, 2009

Scientists discuss in 'Mast cell degranulation contributes to susceptibility to Leishmania major' new findings in life sciences. "Leishmaniasis causes high morbidity and mortality in tropical and subtropical areas. Mast cells can be activated by Leishmania or Leishmania products in vitro and in vivo," researchers in Criciuma, Brazil report.

"Several innate immunity mediators, including some released by mast cells, play roles in the outcome of the disease. In this study, we examined whether pharmacological inactivation of mast cells before infection with L. major interferes with the progressive disease in BALB/c mice. The results show that, when mast cells are...

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Source: TB and Outbreaks Week (2009-03-10)

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