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TB & Outbreaks Week

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Bird Flu



Research from Y. Su and co-researchers in the area of bird flu published



March 10th, 2009

"Binding to and infection of human cells is essential for avian influenza virus transmission. Since virus binding is not always predictive for efficient infection of the cells, here we wished to investigate how hemagglutinin (HA) mutations of avian influenza virus H5N1 influence virus post-binding events in a single cycle of replication," researchers in Beijing, People's Republic of China report.

"One mutation observed in H5 HA of avian and natural human isolates from mainland China, Hong Kong, Vietnam and Thailand was identified and analyzed. The effects of the mutation on receptor binding, fusion and virus entry into cultured cells were investigated using...


Source: TB & Outbreaks Week (2009-03-10)

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