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TB & Outbreaks Week

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Neutropenia



Recent studies by M. Cuencaestrella and co-authors add new data to neutropenia findings



March 17th, 2009

According to recent research published in the Journal of Clinical Microbiology, "A study was designed to assess the reliability of the serial detection of Aspergillus sp. DNA to diagnose invasive aspergillosis (IA) in patients with febrile neutropenia."

"Two blood and two serum samples were taken weekly from 83 patients. A total of 2,244 samples were analyzed by real-time quantitative PCR. Twelve (14.4%) patients were diagnosed with IA. Taking two consecutive positive results as the diagnostic criterion, PCR detected 11 cases, with 4 false positives, giving sensitivity, specificity, positive, and negative predictive values of 91.6%, 94.4%, 73.3%, and 98.5%,...


Source: TB & Outbreaks Week (2009-03-17)

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