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TB & Outbreaks Week

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Tuberculosis Genetics



Scientists at National Institutes of Health, Department of Medical Sciences target tuberculosis genetics



March 17th, 2009

Data detailed in 'Genome-wide SNP-based linkage analysis of tuberculosis in Thais' have been presented. "Tuberculosis, a potentially fatal infectious disease, affects millions of individuals annually worldwide. Human protective immunity that contains tuberculosis after infection has not been clearly defined," investigators in Nonthaburi, Thailand report.

"To gain insight into host genetic factors, nonparametric linkage analysis was performed using high-throughput microarray-based single nucleotide polymorphism (SNP) genotyping platform, a GeneChip array comprised 59 860 bi-allelic markers, in 93 Thai families with multiple siblings, 195 individuals affected with...


Source: TB & Outbreaks Week (2009-03-17)

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