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TB & Outbreaks Week

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Enzyme Research



Studies conducted at T. Laurent et al on enzyme research recently published



March 24th, 2009

According to a study from Antwerp, Belgium, "We used the cysteine proteinase B (cpb) gene family of the trypanosomatid genus Leishmania as a target to develop rapid, specific, and easy-to-use polymerase chain reaction (PCR) tests to discriminate Leishmania infantum, Leishmania donovani, Leishmania tropica, Leishmania aethiopica, and Leishmania major. Identification of all 5 Old World species and validation of intraspecies variability are features lacking in other species-specific PCRs."

"Amplicon analysis was done oil agarose gels and was further simplified by using an oligochrorriatography dipstick to detect L. infantum and L. donovani products. Because the analytical...


Source: TB & Outbreaks Week (2009-03-24)

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