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Life Sciences
Research from S.R. Ferrarini and co-researchers provides new data on life sciences
March 24th, 2009
"A series of seven limonene beta-amino alcohol derivatives has been regioselectively synthesised in moderate to good yields," scientists in Porto Alegre, Brazil report. "Two of these compounds were found to be significantly effective against in vitro cultures of the Leishmania (Viannia) braziliensis promastigote form in the micromolar range. The activities found for 3b and 3f were about 100-fold more potent than the standard drug, Pentamidine, in the same test, while limonene did not display any activity," wrote S.R. Ferrarini and colleagues. The researchers concluded: "This is the first report of antileishmanial activity by limonene beta-amino...
Source: TB & Outbreaks Week (2009-03-24)
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