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Life Sciences
Scientists at University of Stellenbosch describe research in life sciences
March 24th, 2009
"South Africa has one of the highest incidences of multidrug-resistant tuberculosis (MDR-TB) in the world. Concomitantly, aminoglycosides are commonly used in this country as a treatment against MDR-TB," scientists in Cape Town, South Africa report. "To date, at least five mutations are known to confer susceptibility to aminoglycoside-induced hearing loss. The aim of the present study was to develop a rapid screening method to determine whether these mutations are present in the South African population. A multiplex method using the SNaPshot technique was used to screen for five mutations in the MT-RNRI gene: AI555G, CI494T, TI095C, 961deIT+C(n) and A827G. A total of...
Source: TB & Outbreaks Week (2009-03-24)
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