TB & Outbreaks Week
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Tuberculosis
Research on tuberculosis published by scientists at Florida State University
March 24th, 2009
"The structural characterization of small integral membrane proteins pose a significant challenge for structural biology because of the multitude of molecular interactions between the protein and its heterogeneous environment. Here, the three-dimensional backbone structure of Rv1761c from Mycobacterium tuberculosis has been characterized using solution NMR spectroscopy and dodecylphosphocholine (DPC) micelles as a membrane mimetic environment," scientists writing in the journal Protein Science report. "This 127 residue single transmembrane helix protein has a significant (10 kDa) C-terminal extramembranous domain. Five hundred and ninety distance, backbone...
Source: TB & Outbreaks Week (2009-03-24)
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