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TB & Outbreaks Week

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HIV/AIDS Co-Infection



Research data from H. Sarrazin and colleagues update understanding of HIV/AIDS co-infection



March 31st, 2009

According to a study from Borstel, Germany, "Lack of reactivity to the tuberculin skin test (TST) is widely observed in individuals with advanced human immunodeficiency virus type 1 (HIV-1) infection. Biopsy specimens from the TST reaction site and from skin not infiltrated with purified protein derivative were obtained from 15 HIV-1-infected and 23 uninfected persons who did not have active tuberculosis and who were from a community in which the incidence of tuberculosis was very high."

"Histologic sections (size, 8 mu m) were immunohistochemically stained for CD4, CD8, CD28, CD45RA, CD45RO, CD62L, CD1a, human leukocyte antigen (HLA)-DR, granulysin, interferon-gamma,...


Source: TB & Outbreaks Week (2009-03-31)

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