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Arthritis
Studies from University of Louvain describe new findings in arthritis
March 31st, 2009
In this recently published article, scientists in Louvain, Belgium conducted a study "To investigate the role of interleukin-22 (IL-22) in collagen-induced arthritis (CIA), an animal model of rheumatoid arthritis. C57BL/6 mice were immunized with type II collagen (CII) in Freund's incomplete adjuvant with added Mycobacterium tuberculosis, and levels of IL-22 and its specific receptor, IL-22 receptor type I (IL-22RI), were measured in sera and tissue by enzyme-linked immunosorbent assay and real-time quantitative polymerase chain reaction analysis." "Clinical and histologic signs of arthritis were recorded and compared with those in C57BL/6 mice deficient in the IL-22...
Source: TB & Outbreaks Week (2009-03-31)
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