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TB & Outbreaks Week

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Enzyme Research



New enzyme research study findings recently were published by researchers at Duke University



April 7th, 2009

According to a study from the United States, "Diesel exhaust particles (DEPs) are globally relevant air pollutants that exert a detrimental human health impact. However, mechanisms of damage by DEP exposure to human respiratory health and human susceptibility factors are only partially known."

"Matrix metalloproteinase-1 (MMP-1) has been implied as an (etio)pathogenic factor in human lung and airway diseases such as emphysema, chronic obstructive pulmonary disease, chronic asthma, tuberculosis, and bronchial carcinoma and has been reported to be regulated by DEPs. We elucidated the molecular mechanisms of DEPs' up-regulation of MMP-1. Using permanent and primary human...


Source: TB & Outbreaks Week (2009-04-07)

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