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Tuberculosis
Researchers from Chungnam National University, Medical Department detail new studies and findings in the area of tuberculosis
April 7th, 2009
"The 30-kDa antigen (Ag) of Mycobacterium tuberculosis (M. tuberculosis) is a strong inducer of innate and adaptive immune responses in human tuberculosis. The generation of reactive oxygen species (ROS) plays an important role in inflammatory signaling as well as antimicrobial defense," scientists writing in the Journal of Clinical Immunology report. "In this study, we investigated the role of ROS in the activation of mitogen-activated protein kinases (MAPKs) and secretion of the CXC chemokine ligand 8 (CXCL8) and CC chemokine ligand 2 (CCL2) by human monocytes stimulated with the 30-kDa Ag of M. tuberculosis H37Rv. Treatment of human monocytes with the 30-kDa...
Source: TB & Outbreaks Week (2009-04-07)
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