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TB & Outbreaks Week

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Tuberculosis



Studies from A. Jain et al further understanding of tuberculosis



April 7th, 2009

"Ethambutol (EMB) resistance, thought to be occurring due to mutations in embB gene of Mycobacterium tuberculosis on the rise is a cause of grave concern. The present study was planned to investigate the presence of EMB resistance in M. tuberculosis isolates and to look for prevalent mutations in embB gene," investigators in Lucknow, India report.

"A total of 591(283 from new and 308 from previously treated cases) sputum samples from the same number of pulmonary tuberculosis cases were cultured. Isolates were tested by I per cent proportion method for resistance to isoniazid; rifampicin streptomycin and ethambutol. Minimum inhibitory concentration (MIC) of EMB was...


Source: TB & Outbreaks Week (2009-04-07)

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