TB & Outbreaks Week
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Drug Resistance
Studies from University of Wisconsin describe new findings in drug resistance
April 14th, 2009
"Viomycin and capreomycin ore members of the tuberactinomycin family of antituberculosis drugs. As with many antibacterial drugs, resistance to the tuberactinomycins is problematic in treating tuberculosis; this makes the development of new derivatives of these antibiotics to combat this resistance of utmost importance," investigators in the United States report. "To take steps towards developing new derivatives of this family of antibiotics, we have focused our efforts on understanding how these antibiotics are biosynthesized by the producing bacteria so that metabolic engineering of these pathways can be used to generate desired derivatives. Here we present the...
Source: TB & Outbreaks Week (2009-04-14)
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