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TB & Outbreaks Week

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Escherichia Coli



Research from University of Melbourne provide new insights into Escherichia coli



April 14th, 2009

According to recent research published in the journal Emerging Infectious Diseases, "Most Shiga toxin-producing Escherichia coli (STEC) infections that are associated with severe sequelae such as hemolytic uremic syndrome (HUS) are caused by attaching and effacing pathogens that carry the locus of enterocyte effacement (LEE). However, a proportion of STEC isolates that do not carry LEE have been associated with HUS."

"To clarify the emergence of LEE-negative STEC, we compared the genetic composition of the virulence plasmids pO113 and pO157 from LEE-negative and LEE-positive STEC, respectively. The complete nucleotide sequence of pO113 showed that several plasmid...


Source: TB & Outbreaks Week (2009-04-14)

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