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TB & Outbreaks Week

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Tuberculosis



New tuberculosis research from S. Greco and colleagues discussed



April 14th, 2009

According to recent research from Rome, Italy, "In-house PCR (hPCR) could speed differential diagnosis between tuberculosis (TB) and nontuberculous mycobacterial disease in patients with positive smears and pulmonary infiltrates, but its reported accuracy fluctuates across studies. We conducted a systematic review and meta-analysis of hPCR sensitivity and specificity for smear-positive TB diagnosis, using culture as the reference standard."

"After searching English language studies in MEDLINE and EMBASE, we estimated cumulative accuracy by means of summary receiver operating characteristic analysis. The possible influence of hPCR procedures and study methodological...


Source: TB & Outbreaks Week (2009-04-14)

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